R loops consist of RNA–DNA hybrids that accumulate at preferred regions all over the genome, such as pericentromeric DNA, telomeres, ribosomal DNA or transcription termination regions. R loops are an ...

Loops at the ends of telomeres play a vital protective role preventing damage to chromosomes, according to new research. The study showed how the winding and unwinding of 't-loops' at the end of ...

Loops at the ends of telomeres play a vital protective role preventing irretrievable damage to chromosomes, according to new research from the Crick. The study, published in Nature, showed how the ...

In theory of topological LA-semigroups, we introduce the concepts of LA-loop functions for LA-lifting functions in theory of LA-fibrations. We prove that the LA-lifting function and LA-loop function ...

CTCF is widely recognized for its essential role in mediating chromatin loops to regulate gene expression, particularly by modulating enhancer-promoter (EP) interactions. However, acute depletion of ...